Rescue Bowel Preparation: Same Day 2 L Polyethylene Glycol Addition, Not Superior to Bisacodyl Addition 7 Days Later.

Autor: Kim, Jong, Han, Jeung, Boo, Sun-Jin, Ko, Ock, Park, Soo-Kyung, Park, Sang, Yang, Dong-Hoon, Jung, Kee, Kim, Kyung-Jo, Ye, Byong, Myung, Seung-Jae, Yang, Suk-Kyun, Kim, Jin-Ho, Byeon, Jeong-Sik
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Zdroj: Digestive Diseases & Sciences; Sep2014, Vol. 59 Issue 9, p2215-2221, 7p
Abstrakt: Background: The optimal colon-cleansing method after failure of bowel preparation (BP) for colonoscopy has not been established. Aims: We aimed to compare BP rescue methods after failed initial BP and to identify risk factors for rescue BP failure. Methods: Eighty-five patients with BP failure after 4 L polyethylene glycol (PEG) ingestion were prospectively enrolled from March 2008 to March 2012. A second colonoscopy was performed either on the same day after ingestion of another 2 L PEG (group A) or 1 week later after ingestion of 4 L PEG plus 20 mg oral bisacodyl (group B). Differences between groups in terms of BP quality and risk factors for a poor BP on the second colonoscopy were investigated. Results: Median patient age was 59 years, 45 were male (52.9 %), and 17 (20 %) had poor BP on the second colonoscopy. For group B, the multivariable-adjusted odds ratio (OR) for poor BP on the second colonoscopy relative to group A was 0.68 (95 % confidence interval [CI], 0.16-2.95). Adequately ingested PEG during the initial colonoscopy was associated with poor BP on the second colonoscopy (OR 4.05; 95 % CI 1.04-15.75). The two groups had similar patient discomfort rates during the second BP. Conclusions: The two groups did not differ in rescue BP failure rate. Initial BP failure after adequate consumption of 4 L PEG may be a risk factor for rescue BP failure. A stricter BP regimen should be considered for these patients. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index