| Autor: |
Camarinha ‐ Silva, Amélia, Jáuregui, Ruy, Chaves ‐ Moreno, Diego, Oxley, Andrew P.A., Schaumburg, Frieder, Becker, Karsten, Wos ‐ Oxley, Melissa L., Pieper, Dietmar H. |
| Předmět: |
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| Zdroj: |
Environmental Microbiology; Sep2014, Vol. 16 Issue 9, p2939-2952, 14p |
| Abstrakt: |
The anterior nares are an important reservoir for opportunistic pathogens and commensal microorganisms. A barcoded Illumina paired-end sequencing method targeting the 16 S ribosomal RNA V1-2 hypervariable region was developed to compare the bacterial diversity of the anterior nares across distinct human populations (volunteers from Germany vs a Babongo Pygmy tribe, Africa). Of the 251 phylotypes detected, 231 could be classified to the genus level and 109 to the species level, including the unambiguous identification of the ubiquitous S taphylococcus aureus and M oraxella catarrhalis. The global bacterial community of both adult populations revealed that they shared 85% of the phylotypes, suggesting that our global bacterial communities have likely been with us for thousands of years. Of the 34 phylotypes unique to the non-westernized population, most were related to members within the suborder M icrococcineae. There was an even more overwelming distinction between children and adults of the same population, suggesting a progression of a childhood community of high-diversity comprising species of M oraxellaceae and S treptococcaceae to an adult community of lower diversity comprising species of P ropionibacteriaceae, C lostridiales Incertae Sedis XI, C orynebacteriaceae and S taphylococcaceae. Thus, age was a stronger factor for accounting for differing bacterial assemblages than the origin of the human population sampled. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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