| Autor: |
Marangell, Lauren B., Martinez, James M., Zboyan, Holly A., Kertz, Barbara, Seung Kim, H. Florence, Puryear, Lucy J. |
| Předmět: |
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| Zdroj: |
American Journal of Psychiatry; May2003, Vol. 160 Issue 5, p996, 3p, 1 Chart |
| Abstrakt: |
Objective: This study was an evaluation of the omega-3 fatty acid docosahexaenoic acid (DHA) for the treatment of major depression. Method: Thirty-six depressed patients were randomly assigned to receive DHA, 2 g/day, or placebo for 6 weeks. Response was defined a priori as a ≥50% reduction in the score on the Montgomery-Åsberg Depression Rating Scale. Thirty-five participants were evaluable; 18 received DHA, and 17 received placebo. Results: Response rates were 27.8% in the DHA group and 23.5% in the placebo group. The difference in response rates between groups did not reach statistical significance. Conclusions: This trial failed to show a significant effect of DHA monotherapy in subjects with major depression. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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