Novel Mechanisms of Action of Three Antiepileptic Drugs, Vigabatrin, Tiagabine, and Topiramate.

Autor: Ängehagen, Mikael, Ben-Menachem, Elinor, Rönnbäck, Lars, Hansson, Elisabeth
Předmět:
Zdroj: Neurochemical Research; Feb2003, Vol. 28 Issue 2, p333, 8p, 3 Black and White Photographs
Abstrakt: Describes the mechanisms of action of the anti-epileptic drugs vigabatrin, tiagabine and topiramate. Background on epilepsy, a chronic central nervous system (CNS) functional disturbance that manifest by recurrent seizures and induced by abnormal electrical discharges within the CNS; Functions of vigabatrin as a gamma aminobutyric acid-transaminase inhibitor.
Databáze: Complementary Index