Modulation of Leukocyte Recruitment and IL-8 Expression by the Membrane Attack Complex of Complement (C5b-9) in a Rabbit Model of Antigen-Induced Arthritis.

Autor: Tramontini, Nicole L., Kuipers, Paul J., Huber, Colleen M., Murphy, Kerri, Naylor, Keith B., Broady, Autumn J., Kilgore, Kenneth S.
Předmět:
Zdroj: Inflammation; Dec2002, Vol. 26 Issue 6, p311, 9p, 4 Black and White Photographs, 6 Graphs
Abstrakt: Elucidates the role of the membrane attack complex (MAC) in mediating the pathogenesis of antigen-induced arthritis, using rabbits deficient in the complement protein C6. Assessment of swelling, leukocyte accumulation, IL-8 expression, proteoglycan, and hydroxyroline; Analysis of synovial tissue.
Databáze: Complementary Index