Biologically erodable microspheres as potential oral drug delivery systems.

Autor: Mathiowitz, Edith, Jacob, Jules S.
Předmět:
Zdroj: Nature; 3/27/1997, Vol. 386 Issue 6623, p410, 5p, 5 Color Photographs, 7 Black and White Photographs, 2 Graphs
Abstrakt: Demonstrates that engineered polymer microspheres made of biologically erodable polymers, can transverse both the mucosal absorptive epithelium and the follicle-associated epithelium covering the lymphoid tissue of Peyer's patches. The demonstration that these microspheres increase the absorption of three model substances of widely different molecular size.
Databáze: Complementary Index