Does multiple sclerosis affect glucose tolerance?

Autor: Wens, I, Dalgas, U, Deckx, N, Cools, N, Eijnde, BO
Předmět:
Zdroj: Multiple Sclerosis Journal; Aug2014, Vol. 20 Issue 9, p1273-1276, 4p
Abstrakt: Based on current literature, it is not clear if multiple sclerosis (MS) patients are at increased risk to develop impaired glucose tolerance (IGT). Eighty-one MS patients and 45 healthy controls (HC) performed an oral glucose tolerance test. IGT was defined as a fasting glucose concentration of 6.1–6.9 mmol/l and two-hour post-load glucose of 7.8–11.1 mmol/l. The prevalence of impaired fasting glucose concentrations (17% vs 2%) and IGT (11% vs 0%) was higher in MS patients than HC. Accordingly, the areas under the glucose and insulin curves were higher in MS patients. The current study demonstrates an elevated IGT-prevalence in MS. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index