| Abstrakt: |
Cerebral venous sinus thrombosis (CVST) is a rare and potentially deadly condition. Common etiologies include hypercoagulable diseases, low flow states, dehydration, adjacent infectious processes, oral contraceptives, hormonal replacement therapy, pregnancy, and puerperium. Symptoms include nausea, seizures, severe focal neurological deficits, coma, and headache. Anticoagulation is the mainstay of treatment. A series of patient with CVST treated in the department of Neurosurgery, Bir hospital and OM hospital , and to discuss the risk factors, presentation, and outcome of the disease process. This is a case series study, both retrospective and prospective, which was carried out in the department of Neurosurgery, Bir hospital and OM hospital during September 2008 to January 2012. Demographic features like age, sex were analyzed. Thirty six patients were identified over a period of about 3 and a half years. The presenting symptoms included headache (34 patients), vomiting (16 patients),loss of consciousness (14 patients),focal neurological deficit(6 Patients),seizure(6 Patients) and neck pain (2 patients). Signs found included papilloedema (8 patients), fever (4 patients), slurring of speech(2 Patients) and focal neurological signs(4 patients). The most common underlying condition was dehydration and use of estrogen containing contraceptives. All cases received heparin or LMWH followed by Warfarin. One patient who had CVST associated with pituitary adenoma died. CVST has non-specific presenting features and a high risk of morbidity. Although heparin is the mainstay of treatment, there is insufficient evidence to recommend the routine use of thrombolysis at present. [ABSTRACT FROM AUTHOR] |
