Determination of Arbutin, Niacinamide, and Adenosine in Functional Cosmetic Products by High-Performance Liquid Chromatography.

Autor: Jeon, JongSup, Lee, MyoungJin, Yoon, MiHye, Park, Jin-A, Yi, Hee, Cho, Hee-Jung, Shin, Ho-Chul
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Zdroj: Analytical Letters; Jul2014, Vol. 47 Issue 10, p1650-1660, 11p
Abstrakt: A reversed-phase high-performance liquid chromatography method using a diode array detector at 260 nm was developed and validated for the determination of arbutin, niacinamide, and adenosine in cosmetics. The analytes were extracted using methanol and deionized water. The separations were performed on a C18column with gradient elution. At the optimized conditions, the limits of detection for arbutin, niacinamide, and adenosine were 0.75, 0.12, and 0.01 µg/mL, respectively. The average recoveries were between 98.1% and 107.5%. The method was used to analyze thirty cosmetics. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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