| Autor: |
Adedeji, Ahmed A., Ganiyu, Abideen A., Kamyuka, Fredrick K., Rukundo, Godfrey Z., Oonge, Benjamin, Namulema, Jackie, Barigye, Celestine, Yusuf, Sadiq, Vicente-Crespo, Marta |
| Předmět: |
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| Zdroj: |
Clinical Neuropsychiatry; Apr2014, Vol. 11 Issue 2, p68-75, 8p |
| Abstrakt: |
Objective: Mental, Neurologic and Substance use (MNS) disorders constitute substantial burden with increasing public health concern, especially in sub-Saharan Africa. We retrospectively investigated the prevalence of MNS disorders and described the pattern of presentations, age dependent characteristics and response to therapy of patients in a tertiary hospital in Uganda. Method: Between December 2009-March 2012, 822 of 33,069 (2.5%) patients attending the General Out-Patients clinic with signs and symptoms compatible with MNS disorders as described in DSM IV were enrolled into the study. Information regarding their demographic parameters, physical and clinical examinations reports, diagnosis, treatment regimen and follow-up reports were assessed. Results: The order of prevalence of MNS disorders in the population studied were psychosis (40.5%), schizophrenia (29.6%), depression (14.0%), substance abuse (9.2%) and epilepsy (3.7%). Infections and alcohol abuse were among other factors associated with psychosis. A significant mean age differential (P= 0.0001) was observed in the population with one or more MNS disorders affecting 46% (n=336) aged 25-39.9 years and 28.1% student age population. Early onset of psychosis, schizophrenia and depression occur in 7, 9 and 22 patients aged 12-17.9 years respectively. Admission for response monitoring and follow-up treatments was recorded in 440 patients (60.4%) and in 132 patients (18.3%) with repeated admission. Psychosis and schizophrenia were common causes of admission and re-admission. The mean drug prescription was 3.0 + 0.8 (range 1-5) of neuropsychotropics and length of hospital admission ranged from 1-203 days. Remission Time (RT) for these disorders was significantly longer with schizophrenia than psychosis and depression (P= 0.001). Conclusions: MNS disorders affect all ages, especially the productive population and the burden may be under- appreciated. The cost of hospital admissions and delayed desired therapeutic recovery may further deepen neuropsychiatric sequels and poverty in poor resource communities; hence more robust therapeutic and alternative care strategies are required. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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