Two Protocols to Measure Mitochondrial Capacity in Women and Adolescent Girls: A 31P-MRS Preliminary Study.
| Autor: | Willcocks, Rebecca Jane, Fulford, Jon, Barker, Alan Robert, Armstrong, Neil, Williams, Craig Anthony |
|---|---|
| Předmět: |
NUCLEAR magnetic resonance spectroscopy
ISOMETRIC exercise ANALYSIS of variance ANTHROPOMETRY COMPARATIVE studies EXERCISE physiology EXERCISE tests MATHEMATICS MEDICAL protocols PHOSPHOCREATINE STATISTICS T-test (Statistics) ADOLESCENT health TIME WOMEN'S health PILOT projects DATA analysis COOLDOWN REPEATED measures design ERGOMETRY DATA analysis software DESCRIPTIVE statistics ADOLESCENCE |
| Zdroj: | Pediatric Exercise Science; May2014, Vol. 26 Issue 2, p210-217, 8p |
| Abstrakt: | The phosphocreatine (PCr) recovery time constant (τ) following exercise provides a measure of mitochondrial oxidative capacity. The purpose of this investigation was to use 2 different protocols to determine τ in adolescent females. 31P-MR spectra were collected during 2 exercise tests in 6 adolescent girls (13.8 ± 0.3 y) and 7 women (23.2 ± 3.4 y). The first test consisted of 23 repeated 4 seconds maximal isometric calf contractions separated by 12-second recovery; PCr recovery between the final 18 contractions was used to calculate τ. The second test was a sustained 20-second maximal contraction; recovery was fitted with an exponential function to measure τ. PCr τ did not significantly differ between groups: (gated exercise: 4 girls: 16 ± 5 s, 7 women: 17 ± 5 s, p; sustained exercise: 6 girls: 19 ± 6 s, 7 women: 19 ± 4 s). Bland-Altman analysis demonstrated a close agreement between sustained and gated exercise. Both gated and sustained exercise appear feasible in a pediatric population, and offer a noninvasive evaluation of mitochondrial oxidative capacity. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
| Externí odkaz: |
|