| Autor: |
Roopesh Kumar, V., Madhugiri, Venkatesh, Sasidharan, Gopalakrishnan, Shankar Ganesh, C., Gundamaneni, Sudheer |
| Předmět: |
|
| Zdroj: |
European Spine Journal; May2014 Supplement, Vol. 23, p236-241, 6p, 5 Diagrams, 1 Chart |
| Abstrakt: |
Purpose: Primary intraosseous spinal malignant peripheral nerve sheath tumor (MPNST) is exceedingly rare. MPNST with multifocal origin has been described to occur in the extremities. Such a lesion has not been described to occur in the spine. We describe a case of multifocal spinal MPNST and to review the literature relevant to this rare entity and its management. Methods: A 40-year-old immunodeficient patient presented with rapidly progressive paraparesis and mid back ache. Results: Despite aggressive surgical decompression, he developed multiple metastases 3 months after surgery. However, he remained stable for 1 year without any adjuvant therapy. Presently, he has received palliative radiotherapy for spinal recurrence and cerebral metastasis. Conclusion: Multifocal spinal MPNST is a rare lesion. In this instance, the multifocality of the disease and its odd location could be attributed to the immunodeficiency state. The prolonged survival could be due to an improvement in his immune status due to HAART. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
Full text from SpringerLink