Hippocampal synaptic transmission enhanced by low concentrations of nicotine.

Autor: Gray, Richard, Rajan, Arun S.
Předmět:
Zdroj: Nature; 10/24/1996, Vol. 383 Issue 6602, p713, 4p, 1 Black and White Photograph, 14 Graphs
Abstrakt: Proposes that nicotine from tobacco influences cognition by enhancing synaptic transmission. Nicotine's action upon presynaptic nicotonic acetylcholine receptors (nAChR) within the hippocampus; A possible explanation for the deficits associated with the loss of cholinergic innervation during Alzheimer's disease.
Databáze: Complementary Index