| Autor: |
Ramful, Duksha, Sampériz, Sylvain, Fritel, Xavier, Michault, Alain, Jaffar-Bandjee, Marie-Christine, Rollot, Olivier, Boumahni, Brahim, Gérardin, Patrick |
| Předmět: |
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| Zdroj: |
Journal of Infectious Diseases; Jun2014, Vol. 209 Issue 11, p1726-1730, 5p |
| Abstrakt: |
To search for serological evidence of congenital infection in apparently healthy neonates born to women infected with the Chikungunya virus (CHIKV) during pregnancy, monitoring for CHIKV-specific antibodies was performed within the CHIMERE cohort study (Reunion island, 2006–2008). CHIKV-specific antibody kinetics showed no evidence of asymptomatic congenital infection as neonates were tested negative for CHIKV-specific IgM antibodies at birth and 368 infants with CHIKV-specific IgG antibodies seroreversed completely (mean seroreversion time: 7.7 months). Seroreversion time of transplacental CHIKV IgG antibodies was inversely correlated with the stage of pregnancy at which exposure took place and end-term small for gestational infants seroreversed earlier. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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