An agent cleaving glucose-derived protein crosslinks in vitro and in vivo.
| Autor: | Vasan, Sara, Zhang, Xin |
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| Zdroj: | Nature; 7/18/1996, Vol. 382 Issue 6588, p275, 4p, 3 Black and White Photographs, 2 Diagrams, 5 Graphs |
| Abstrakt: | Describes a prototypic crosslink `breaker,' relating to the class of products known as advanced-glycation end-products (AGE). Investigation of a potential pharmacological strategy for selectively cleaving the resultant glucose-derived protein crosslinks; Work on in vitro and in vivo situations. |
| Databáze: | Complementary Index |
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