| Abstrakt: |
Nutritional secondary hyperparathyroidism (NSH) is a common disease in kittens in Iran. It occurs due to malnutrition with clinical signs of anorexia, lameness and irregularity in the vertebral column and long bones. In humans, hypomagnesaemia has been found to be associated with hyperparathyroidism. An association of copper deficiency with hypocalcaemia and the radiographic features of rickets and hyperparathyroidism have also been described in human infants. In humans, urinary excretion of copper and zinc is greater than normal in patients with untreated primary hyperparathyroidism. This survey was performed based on clinical, radiographic and laboratory findings to measure serum copper and magnesium in kittens suffering from NSH. A total of 27 kittens were diagnosed with NSH based on history, clinical examinations and radiographic findings. In addition, 10 healthy kittens were studied as controls. According to the radiographic findings, affected kittens were classified as having mild, moderate and severe NSH. They were also classified, based on age, into four groups (2-3, 3-4, 4-5 and 5-6 months). Total serum calcium, phosphorus, copper and magnesium were measured as biochemical parameters. Serum copper and magnesium were significantly lower in severe, moderate and mild cases with dietary osteoporosis in comparison to controls ( p < 0.05). NSH was most prevalent in cats between 2 and 3 months. No significant difference was found between males and females. Our data suggest that hypomagnesaemia and copper deficiency are associated with NSH in cats. Much still remains to be learnt about the exact role of magnesium and copper in cats suffering of NSH. [ABSTRACT FROM AUTHOR] |
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