ENDOCRINE CHANGES IN A MECHANICALLY VENTILATED GIRL WITH ANOREXIA NERVOSA.

Autor: Chiru, Daniela, Crăciun, A., Tepeneu, N. F., Popoiu, C., Grecu, Alina, Daescu, Camelia, Marcovici, Tamara, Marginean, Otilia
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Zdroj: Jurnalul Pediatrului; Jul-Sep2013, Vol. 16 Issue 63, p57-60, 4p
Abstrakt: Introduction: Anorexia nervosa (AN) is an eating disorder and also a psychiatric disorder, characterized by a weight well below the standard weight due to a distorted image of the body with obsessive fear of weight gain. Material and method: We present the case of a 10 years old girl weighing 16 kg (body mass index BMI = 8.16 kg/m2), who was hospitalized in the Pediatric Clinic for loss of appetite, inability to walk and maintain orthostatism, with motor deficit on the right side of the body. The onset was affirmative five months ago, after separation from the mother (gone abroad), the child being left in the care of a grandmother. Twenty-four hours after admission, the girl experienced periods of voluntary apnea, requiring endotracheal intubation and mechanical ventilation. Results: Endocrine balance showed in this case: elevated cortisol levels, low levels of follicle stimulating hormone (FSH), estradiol and testosterone; high levels of growth hormone (GH) and low levels of insulin-like growth factor (IGF-I); low levels of thyroid hormones (T3 and T4) and slightly decreased thyroid-stimulating hormone (TSH). During the 96 days of hospitalization, the patient required the placement of a tube tracheostomy to continue mechanical ventilation and a PEG (percutaneous endoscopic gastrostomy tube) for enteral nutrition. Weight gain was 4 kg. The patient died due to infectious complications after 6 months following hospitalization in another center. Conclusions: Endocrine changes that occur in AN are secondary to physiological adaptation of the body to a state of starvation. AN and the associated malnutrition that occurs through self-imposed starvation can cause severe organic and psychological complications and can even lead to death. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index