| Abstrakt: |
Mannich reactions of 6-methyl-1-(thietan-3-yl)pyrimidine-2,4(1 H,3 H)-dione with formaldehyde and morpholine, piperidine, N-methylpiperazine, and diethylamine gave the corresponding 5-aminomethylsubstituted pyrimidine derivatives. The title compound reacted with excess piperazine to form 3,5-bis-(piperazin-1-yl) derivative, while its reaction with an equimolar amount of piperazine afforded 5,5′-(piperazin-1,4-diylbismethylene)bis[6-methyl-1-(thietan-3-yl)pyrimidine-2,4(1 H,3 H)-dione]. [ABSTRACT FROM AUTHOR] |
