| Autor: |
Padrnos, L.J., Blair, J.E., Kusne, S., DiCaudo, D.J., Mikhael, J.R. |
| Předmět: |
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| Zdroj: |
Transplant Infectious Disease; Apr2014, Vol. 16 Issue 2, p307-314, 8p |
| Abstrakt: |
Discrete nodules developed on the leg of a 27-year-old immunosuppressed woman after an allogeneic stem cell transplant. Biopsy and culture grew Legionella pneumophila serogroup 8. On day 7 of azithromycin treatment, respiratory distress and abnormal liver transaminases developed, and the patient died on day 14. Review of the medical literature identified 19 reports of Legionella species-associated skin or soft tissue infections (total of 20 patients, 13 with confirmed infection). Manifestations of the 13 confirmed cases included erythematous macular rash ( n = 7), erythema after thoracentesis ( n = 1), abscess formation ( n = 4), respiratory symptoms ( n = 6), and abnormal chest radiographs ( n = 8). Six required surgical exploration and débridement, and 7 were immunocompromised. Rash and respiratory infection improved with antibiotics in 10, but 3 died. Immunosuppression may predispose transplant recipients to Legionella infections. Diagnostic biopsies may facilitate appropriate treatment. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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