Dawning of the epigenetic era in hereditary cancer.

Autor: Hitchins, M.P., Lynch, H.T.
Předmět:
Zdroj: Clinical Genetics; May2014, Vol. 85 Issue 5, p413-416, 4p
Abstrakt: The article comments on research studies on Lynch syndrome. It specifically discusses the molecular basis for the syndrome and the role of epigenetic mechanisms in the pathogenesis of this high-risk hereditary cancer syndrome. It also discusses a study devised clinical criteria for the original clinic-based diagnosis of Lynch syndrome.
Databáze: Complementary Index