Regioselective Synthesis of Functionally Crowded Benzenes at Room Temperature through Ring Transformation of 2H-Pyran-2-ones.

Autor: Singh, Fateh Veer, Kumar, Vijay, Goel, Atul
Předmět:
Zdroj: Synlett; 2007, Issue 13, p2086-2090, 5p
Abstrakt: An expeditious synthesis of highly substituted benzenes with electron-withdrawing or electron-donating substituents is �described and illustrated by carbanion-induced ring transformation of 2H-pyran-2-one with malononitrile in excellent yield. The �novelty of the reaction lies in the creation of an aromatic ring at room temperature from a six-membered lactone under mild reaction conditions. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index