An Efficient Synthesis of N-Arylputrescines and Cadaverines.

Autor: Link, Natalia P., D�az, Jimena E., Orelli, Liliana R.
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Zdroj: Synlett; 2009, Issue 5, p751-754, 4p
Abstrakt: We present a two-step, general synthesis of N-aryl�putrescines and cadaverines, by cesium carbonate mediated alkylation of anilines with ω-chloronitriles and subsequent reduction. The cesium-mediated alkylation shows remarkable selectivity towards the monoalkylation product. The method is straightforward and leads to satisfactory global yields. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index