Autor: |
Russo, Alessio, Botta, Giovanna, Lattanzi, Alessandra |
Předmět: |
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Zdroj: |
Synlett; 2007, Issue 5, p0795-0799, 5p |
Abstrakt: |
Amides easily obtained from enantiopure (R)- and (S)-NOBIN and l-proline have been shown to promote the enantioselective direct aldol reaction under low catalytic loadings (5 mol%), in apolar hexane as the solvent and using only a slightly higher �molar excess of the acetone with respect to the aldehyde. Aldol products are isolated in good to high yields and up to 77% ee at room temperature. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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