Prenatal Detection of Fetal Growth Restriction in Newborns Classified as Small for Gestational Age: Correlates and Risk of Neonatal Morbidity.
| Autor: | Chauhan, Suneet P., Beydoun, Hind, Chang, Eugene, Sandlin, Adam T., Dahlke, Josh D., Igwe, Elena, Magann, Everett F., Anderson, Kristi R., Abuhamad, Alfred Z., Ananth, Cande V. |
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| Předmět: |
DISEASE risk factors
FETAL growth retardation INFANT mortality BIRTH size CHI-squared test CONFIDENCE intervals LONGITUDINAL method MEDICAL cooperation POISSON distribution PRENATAL diagnosis REGRESSION analysis RESEARCH T-test (Statistics) DATA analysis software DESCRIPTIVE statistics CHILDREN DIAGNOSIS MORTALITY risk factors |
| Zdroj: | American Journal of Perinatology; 2014, Vol. 31 Issue 3, p187-194, 8p, 3 Charts |
| Abstrakt: | We examined the rate of detecting small for gestational age (SGA; birth weight < 10%) as intrauterine growth restriction (IUGR) prenatally at four centers and determined risks of composite neonatal morbidity (CNM) and mortality among detected versus undetected (no antenatal diagnosis of IUGR). A multicenter cohort study of 11,487 nonanomalous, singleton live births with sonographic exam before 22 weeks was performed. Of 11,487 births, 8% (n = 929) were SGA that met the inclusion criteria, with 25% of them being prenatally detected. The CNM among SGA births that were prenatally detected as IUGR was higher (23.3%) than undetected SGA (9.7%), but this difference was no longer significant following adjustments for confounding factors. Among preterm births (<37 weeks), undetected SGA had significantly higher CNM (risk ratio [RR] 10.0, 95% confidence interval [CI] 6.3, 16.1) for deliveries at 24 to 33 weeks and RR 3.0, 95% CI 1.7, 5.4 for 34 to 36 weeks). In summary, only a quarter of SGA births were detected prenatally as IUGR and among preterm SGA, the CNM is significantly higher when SGA births are undetected as IUGR. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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