Review of Synthesis of Spiro Heterocyclic Compounds from Isatin.

Autor:	Borad, MayuriA., Bhoi, ManojN., Prajapati, NeelamP., Patel, HiteshD.
Předmět:	SPIRO compounds HETEROCYCLIC compounds synthesis ISATIN ORGANIC synthesis CARBONYL group RING formation (Chemistry) ZWITTERIONS
Zdroj:	Synthetic Communications; Apr2014, Vol. 44 Issue 7, p897-922, 26p, 58 Diagrams
Abstrakt:	Isatin is an essential building block in organic synthesis and shows various biological activities. The most attractive application of isatin in organic synthesis is undoubtedly in the highly reactive C-3 carbonyl group, which is a prochiral center as well. The construction of a spiroheterocyclic framework has always been a challenging endeavor for synthetic organic chemists as it frequently requires synthetic design based on specific strategies. This review gives a short summary of the advances in the use of isatin in the synthesis of various spiroheterocyclic compounds through multicomponent reactions and 1,3-dipolar cycloaddition reactions. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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