| Abstrakt: |
This study investigated the toxic effects of 12 substituted benzenes exposed to Propsilocerus akamusi larvae singly and as mixtures. Their toxicities were quantified in terms of median effective concentration (EC) killing 50% of the larvae. For individual substituted benzenes to 4th-instar P. akamusi larvae, the toxicity was in decreasing order of p-chlorophenol > nitrobenzene > phenol > 1,2-dimethylbenzene > 1,3-dimethylbenzene > chlorobenzene > p-phenylenediamine > 1,4-dimethylbenzene > m-phenylenediamine > methylbenzene > benzene > aniline. The order of toxicity among three isomers of dimethylbenzene was 1,2-dimethylbenzene > 1,3-dimethylbenzene > 1,4-dimethylbenzene while p-phenylenediamine > m-phenylenediamine. The binary substituted benzene compounds' toxicities were evaluated by toxic unit (TU), additive index (AI), mixture toxicity index (MTI) and similarity parameter index (λ). The evaluation results of TU and MTI for 9 substituted benzene compounds were completely consistent while the results of AI were the same as the results of λ based on 24 h EC of binary substituted benzenes. The evaluation results of 10 substituted benzene compounds were consistent using TU, MTI, AI and λ evaluation methods. 52.63% and 47.37% of binary substituted benzene tests on P. akamusi larvae showed synergism and partial addition/antagonism, respectively, under mixtures of equal proportions. These results suggest that substituted benzenes indicate acute and binary joint toxicity to P. akamusi. [ABSTRACT FROM AUTHOR] |
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