Incidence and diagnosis of ventilator-associated tracheobronchitis (VAT) in the intensive care unit: an international online survey.

Autor: Rodríguez, Alejandro, Póvoa, Pedro, Nseir, Saad, Salluh, Jorge, Curcio, Daniel, Martín-Loeches, Ignacio
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Zdroj: Critical Care; 2014, Vol. 18 Issue 1, p1-23, 23p
Abstrakt: Introduction Several aspects of ventilator-associated tracheobronchitis (VAT) remain poorly defined, including diagnostic criteria, overlap with ventilator-associated pneumonia (VAP) and appropriate treatment regimens. The objective of this study was to survey reported practices in the clinical and microbiological diagnosis of VAT, and to evaluate perceptions of the impact of VAT on patient outcomes. Methods We developed a questionnaire comprising of: 1) Characteristics of the respondent, the ICU and hospital, 2) current clinical and microbiological diagnostic approach, 3) empirical antibiotic therapy and 4) the perception of physicians regarding the clinical impact of VAT and its implications. Results A total of 288 ICUs from 16 different countries answered the survey, 147 (51%) from the Latin American Group (LA) and 141 (49%) from Spain, Portugal and France (SPF group). The majority of respondents (n = 228; 79.2%) reported making the diagnosis of VAT based on clinical and microbiological criteria and 40 (13.9%) by clinical criteria alone. Approximately half (50.3%) of the respondents agreed that patients should receive antibiotics (ATB) for the treatment of VAT. Out of all respondents, 269 (93.4%) assume that a VAT episode increases ICU length of stay and this perception is greater in LA (97.3%) than in SPF group (89.4%, P <0.05). Half of the physicians considered that VAT increases the risk of mortality, and this perception is again greater in LA (58.5% versus 41.1%, P <0.05). Conclusion Given the possible high incidence of VAT and the perception of its importance as a risk factor for VAP and mortality, a large multicentre international prospective study would be helpful to validate a consensual definition of VAT, to determine its incidence and delineate its impact on subsequent VAP occurrence. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index