| Autor: |
Bogden, John D., Bendich, Adrianne, Kemp, Francis W., Bruening, Kay S., Skurnick, Joan H., Denny, Thomas, Baker, Herman, Louria, Donald B. |
| Předmět: |
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| Zdroj: |
American Journal of Clinical Nutrition; Sep1994, Vol. 60 Issue 3, p437-447, 11p |
| Abstrakt: |
A placebo-controlled double-blind trial of the effects of daily micronutrient supplements on circulating vitamin and trace metal concentrations and delayed-hypersensitivity skim test (DHST) responses was conducted. Subjects, aged 59-85 y, were randomly assigned o placebo (n = 27) or micronutrient (n = 29) treatment groups. DHST and circulating concentrations of nine micronutrients were measured before and after 6 and 12 mo of micronutrient ingestion. For the micronutrient group, there were statistically significant increases at 6 and/or 12 mo in the mean serum concentrations of ascorbate, β-carotene, folate, vitamin B-6, and α-tocopherol. There was a significant increase at 12 mo in the number of subjects in the placebo group with one or more low concentrations. DHST responses o a panel of seven recall antigens were significantly increased at 12 mo in the micronutrient group but not the placebo group. This study demonstrates that daily supplementation with low-to-moderate doses of micronutrients can prevent low concentrations of some micronutrients and can improve DHST responses in healthy, independently living olden adults. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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