Assessment of the vitamin A status in lactating and nonlactating, nonpregnant Indonesian women by use of the modified-relative-dose-response (MRDR) test.

Autor: Tanumihardjo, Sherry A., Muherdiyantiningsih, Permaesih, Dewi, Dahro, Ance M., Muhilal, Karyadi, Darwin, Olson, James A.
Předmět:
Zdroj: American Journal of Clinical Nutrition; Jul1994, Vol. 60 Issue 1, p142-147, 6p
Abstrakt: The vitamin A statuses of two groups of Indonesian women were compared by using the modified-relative-dose-response (MRDR) test: 1) lactating, nonpregnant women of lower socioeconomic status (n = 64) and 2) better-educated, pre-menopausal, nonpregnant, nonlactating women (n = 14). At times from 3 to 6 h after dosing, the mean ratio of dehydroretinol to retinol (DR/R) in the serum was approximately threefold higher in the lactating women than in the control group, eg, 0.109 ± 0.073 and 0.034 ± 0.015, respectively, at 5 h. At a provisional DR/R cutoff of 0.06, the vitamin A statuses of 70% of the lactating women and of 7% of the control women were judged to be inadequate. Only 7% of the variability in abnormal MRDR ratios could be attributed to body weight. Both abnormal and normal responses were highly reproducible when performed 0.5-3.25 mo after the first test. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index