Outcome of live and deceased donor renal transplantation in patients aged ≥55 years: A single.center experience.

Autor:	Kute, V. B., Vanikar, A. V., Shah, P. R., Gumber, M. R., Patel, H. V., Modi, P. R., Rizvi, S. J., Shah, V. R., Modi, M. P., Kanodia, K. V., Trivedi, H. L.
Předmět:	CHRONIC kidney failure ACADEMIC medical centers CHI-squared test COMPARATIVE studies DEAD FISHER exact test KIDNEY transplantation ORGAN donors HEALTH outcome assessment SURVIVAL T-test (Statistics) TREATMENT effectiveness DATA analysis software DESCRIPTIVE statistics KAPLAN-Meier estimator LOG-rank test SURGERY
Zdroj:	Indian Journal of Nephrology; Jan/Feb2014, Vol. 24 Issue 1, p9-14, 6p, 1 Chart, 4 Graphs
Abstrakt:	Renal transplantation (RTx) has now become an accepted therapeutic modality of choice for elderly ESRD patients. This single-center study was undertaken to evaluate the outcome of RTx in ESRD patients. ≥5 years. A total of 103 patients underwent RTx 79 living related living donors [LD], 24 deceased donors [DD]) at our center. Post-transplant immunosuppression consisted of calcineurin inhibitor-based regimen. The mean donor age was 58.3 years in the LD group and 59.5 years in the DD group. Male recipients constituted 92% in LD and 75% in DD group. In living donor renal transplantation, 1- and 5-year patient survival was 93% and 83.3% respectively and death-censored graft survival was 97.3% and 92.5% respectively. There were 12.6% biopsy proven acute rejection (BPAR) episodes and 12.6% patients were lost, mainly due to infections. In deceased donor renal transplantation, 1- and 5-year patient survival was 79.1% and 74.5% respectively and death-censored graft survival was 95.8% and 85.1% respectively. There were 12.5% BPAR episodes and 25% of patients were lost, mainly due to infections. RTx in ESRD (≥55 years) patients has acceptable patient and graft survival if found to have cardiac fitness and therefore should be encouraged. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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