Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/Mpr gene.

Autor: Wang, Zhao-Qi, Fung, Marion R.
Předmět:
Zdroj: Nature; 12/1/1994, Vol. 372 Issue 6505, p464, 4p, 10 Color Photographs, 4 Black and White Photographs, 1 Diagram, 2 Charts
Abstrakt: Studies the functions of the receptor for insulin-like growth factor type 2 in mice, also known as the cation-independent mannose-6-phosphate receptor (Igf2/Mpr). Generation of mice lacking the gene; Maternal expression of Igf2/Mpr as essential for late embryonic development and growth regulation; Role for the reactivated paternal allele in postnatal survival.
Databáze: Complementary Index