Activity of DMP 840, a new bis-naphthalimide, on primary human tumor colony-forming units.

Autor: Cobb, Patrick W., Degan, Donna R.
Předmět:
Zdroj: JNCI: Journal of the National Cancer Institute; 10/5/94, Vol. 86 Issue 19, p1462, 4p, 1 Diagram, 3 Charts
Abstrakt: Evaluates DMP 840 bis-naphthalimide in a human tumor clonogenic assay to estimate what plasma concentrations may be necessary for clinical cytotoxic activity and to determine what types of tumors potentially might be primary targets for initial phase II studies. Percentage of specimens tested showing in vitro responses.
Databáze: Complementary Index