MHC class I/beta 2-microglobulin complexes associate with TAP transporters...

Autor: Ortmann, Bodo, Androlewicz, Matthew J.
Předmět:
Zdroj: Nature; 4/28/1994, Vol. 368 Issue 6474, p864, 4p, 9 Color Photographs
Abstrakt: Focuses on major histocompatibility complex (MHC) class I molecules that bind antigenic peptides in the endoplasmic reticulum (ER) and transport them to the cell surface for recognition by cytotoxic T lymphocytes. Generation of peptides from cytoplasmic proteins; Intimacy of antigen processing (TAP) molecules in the assembly of the class I/beta 2-microglobulin peptide complex.
Databáze: Complementary Index