Frameshift mutation, A263fsinsGG, in the hepatocyte nuclear factor-1beta gene associated with diabetes and renal dysfunction.

Autor: Nishigori, Hidekazu, Yamada, Shirou, Kohama, T., Tomura, H., Sho, K., Horikawa, Y., Bell, G.I., Takeuchi, T., Takeda, J., Nishigori, H, Yamada, S
Předmět:
Zdroj: Diabetes; Aug1998, Vol. 47 Issue 8, p1354-1355, 2p, 2 Black and White Photographs, 1 Diagram
Abstrakt: Presents a study of hepatocyte nuclear factor-1alpha (HNF-1alpha) genetic mutations in Japanese subjects with early-onset type 2 diabetes. HNF-1alpha as the cause of one form of maturity-onset diabetes of the young; Suggestion that a263fsinsGG mutations in HNF-1beta gene might be associated with diabetes and renal dysfunction.
Databáze: Complementary Index