NIDDM genes in mice.

Autor: Leiter, Edward H., Reifsnyder, Peter C., Flurkey, Kevin, Partke, Hans-Joachin, Junger, Erika, Herberg, Lieselotte
Předmět:
Zdroj: Diabetes; Aug1998, Vol. 47 Issue 8, p1287, 9p, 4 Charts, 12 Graphs
Abstrakt: Describes how polygenic thresholds for the transition from impaired glucose tolerance to non-insulin dependent diabetes mellitus (NIDDM) are reached using mouse genetics. Identification of a NON-derived diabetogenic locus on chromosome 4; Deleterious synergism between genetic loci from strains; Complexity of the inheritance of obesity-associated forms of NIDDM in humans.
Databáze: Complementary Index