Cloning and characterization of a cAMP-specific cyclic nucleotide phosphodiesterase.

Autor: Soderling, S.H., Bayuga, S.J., Beavo, J.A.
Předmět:
Zdroj: Proceedings of the National Academy of Sciences of the United States of America; 07/21/98, Vol. 95 Issue 15, p8991, 6p, 3 Color Photographs, 1 Black and White Photograph, 1 Diagram, 1 Chart, 1 Graph
Abstrakt: Focuses on a study which cloned and characterized a mouse testis' novel cyclic adenosine 3'-5'-phosphate (cAMP)-specific cyclic nucleotide phosphodiesterases (PDE). Regulation of levels of cAMP by PDE; Roles of cAMP and cyclic guacyclic acid (cGMP) in mediating the biological effects of several first messengers; Methodology used to conduct the study; Results of the study.
Databáze: Complementary Index