Ovarian Sertoli-Leydig cell tumor of intermediate differentiation with immature skeletal muscle heterologous elements.

Autor: Kostopoulou, Evanthia, Talerman, Alexander
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Zdroj: Acta Obstetricia et Gynecologica Scandinavica; Feb2003, Vol. 82 Issue 2, p197-198, 2p
Abstrakt: Sertoli-Leydig cell tumors constitute only 1% of sex cordstromal neoplasms and therefore less than 0.5% of primary ovarian tumors (1), but they often pose diagnostic problems because of their wide spectrum of histologic patterns and appearances. Tumors with a retiform pattern, which usually occur in younger patients (2), or tumors with heterologous elements may mimic a large variety of ovarian neoplasms. A stromal heterologous component is encountered in 5% of all Sertoli-Leydig cell tumors and includes mainly cartilaginous elements and/or immature skeletal muscle (3). The clinical and endocrinological profiles of these tumors are similar to those of Sertoli-Leydig cell tumors without heterologous elements, but the androblastomatous component is almost always poorly differentiated when stromal heterologous elements are present. We have recently encountered a case of Sertoli-Leydig cell tumor of intermediate differentiation exhibiting a heterologous rhabdomyoblastic component, which we are reporting briefly. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index