| Autor: |
Ajmani, Ranjeet S., Fleg, Jerome L., Demehin, A. Andrew, Wright, Jeanette G., O'Connor, Frances, Heim, Jane M., Tarien, Edward, Rifkind, Joseph M. |
| Předmět: |
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| Zdroj: |
Clinical Hemorheology & Microcirculation; 2003, Vol. 28 Issue 1, p29, 12p |
| Abstrakt: |
The present investigation was designed to evaluate the acute effect of aerobic exercise on oxidative stress and the flow properties of the blood. Fourteen clinically healthy subjects (7 men and 7 women aged 56 5 ± 19 yr) underwent maximal treadmill exercise with blood samples drawn prior to and immediately after exercise. Post-exercise significant increases were observed in plasma lipid hydroperoxides from 6.5 5 ± 2.0 μM to 7.9 ± 1.9 μM (p < 0.0001) and the relative concentration of plasma fluorescent products associated with red cell peroxidation from 138 ± 28 RF to 220 ± 92 RF (p < 0.005). After exercise there was a rise in the hematocrit from 41.4 ± 3.7% to 44.4 ± 4.1% (p < 0.0001), increases in whole blood viscosity at shear rates of 22.5/sec to 450/sec (p < 0.0005), an increase in plasma viscosity from 1.27 ± 0.12 cP to 1.36 ± 0.11 cP (p < 0.01), an increase in red cell rigidity from 2.44 ± 0.48 cP to 2.62 ± 0.42 cP (p < 0.001) and a decrease in erythrocyte sedimentation rate from 26.9 ± 18.6 mm/h to 22.5 ± 15.9 mm/h (p < 0.01). The findings suggest that acute aerobic exercise induces oxidative damage to red blood cells and adversely affects rheological properties of the peripheral blood. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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