Resistance to cadmium mediated by ubiquitin-dependent proteolysis.

Autor: Jungmann, Joern, Reins, Hans-Albert
Předmět:
Zdroj: Nature; 1/28/1993, Vol. 361 Issue 6410, p369, 3p, 3 Black and White Photographs, 2 Diagrams
Abstrakt: Shows that expression of the ubiquitin-dependent proteolysis pathway in yeast is activated in response to cadmium exposure and that mutants deficient in specific ubiquitin-conjugating enzymes are hypersensitive to cadmium. Primary structure of the UBC7 gene; Cadmium hypersensitivities of mutants of the ubiquitin-dependent proteolysis system; Increase in the expression of the ubiquitin system in response to cadmium; Further details.
Databáze: Complementary Index