Radiographic evaluation of the effect of obesity on alveolar bone in rats with ligature-induced periodontal disease.

Autor: Do Nascimento, Cassiane Merigo, Cassol, Tiago, Da Silva, Fernanda Soares, Bonfleur, Maria Lucia, Nassar, Carlos Augusto, Nassar, Patricia Oehlmeyer
Předmět:
Zdroj: Diabetes, Metabolic Syndrome & Obesity: Targets & Therapy; 2013, Vol. 6, p365-370, 6p
Abstrakt: There is evidence that the lack of metabolic control of obese patients may accelerate periodontitis. The aim of this study was to evaluate radiographically the effect of cafeteria-diet-induced obesity on alveolar bone loss in rats subjected to periodontal disease. Twenty male Wistar rats were randomly divided into four groups: 1) control group, 2) control and ligature group; 3) cafeteria group; and 4) cafeteria and ligature group. The animals were evaluated for obesity and euthanized, and the mandible of each rat was removed to perform a radiographic evaluation of alveolar bone loss and its effect on diet-induced obesity. The results showed greater alveolar bone loss in the mice in Group 4 (P<0.01). Thus, we concluded that obese mice, on average, showed greater radiographic evidence of alveolar bone loss than mice undergoing induction of obesity. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index