DNA ORIGAM I SITE-SPECIFIC ARRANGEMENT OF GOLD NANOPARTICLES.

Autor: GEORGE, AMOAKO, YE, RIAN, LIZHOU ZHUANG, XIAOHONG YANG, ZHIYONG SHEN, MING ZHOU
Předmět:
Zdroj: NANO; Dec2013, Vol. 8 Issue 6, p1-11, 11p
Abstrakt: Controlling matter at the nanoscale holds a lot of promise in nanotechnology. The DNA origami is promising if used as a template to design and arrange matter at the nanoscale. We have used the DNA origami approach to engineer staple strands at selected sites for attachment of gold nanoparticles. The covalent attachment of thiol-modified DNA oligomers was used to functio-nalize gold nanoparticles. These oligomers then hybridize with complementary strands extended on selected staple strands on the DNA origami surface with nanometer precision. Gold nano-particles of 5 nm diameter were arranged across a DNA origami tube to form a C-shape which has potential use in electronics and plasmonics. Agarose gel electrophoresis, AFM, UV-Vis spec-troscopy and TEM were used to characterize the structure. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index