Integral Approach to Evaluation of the Pathogenic Activity of Trypanosoma Cruzi Clones as Exemplified by the Mexican Strain.

Autor: Melnikov, Valery, Espinoza-Gomez, Francisco, Newton-Sanchez, Oscar, Delgado-Ensiso, Ivan, Montesinos-Lopez, Oswal Antonio, Dalin, M. V., Espinoza, Bertha, Martinez, Ignacio, Sheklakova, L. A., Dobrovinskaya, Oksana, Karpenko, L. P.
Předmět:
Zdroj: Bulletin of Experimental Biology & Medicine; Nov2013, Vol. 156 Issue 1, p70-72, 3p
Abstrakt: Comparative histopathological study and analysis of parasite load in different muscle groups were carried out in BALB/c mice during the acute phase of Chagas disease. Activities of C104 clone of T. cruzi strain TPAP/MX/2002/Albarrada and the parental strain were compared. Panoramic 2D-microscopy imaging of sample surface was used and quantitative analysis of parasitism and pathologic damage was performed. The infection rates in various muscle groups were as follows: myocardium = abdominal muscles = lumbar muscles = femoral muscles ← diaphragm for the clone and myocardium⊣abdominal muscles = lumbar muscles = femoral muscles → diaphragm for the parental strain. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index