Sequence variations in the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene: identification of 10 novel single nucleotide polymorphisms (SNPs) and analysis of their relevance to morphine glucuronidation in cancer patients.
| Autor: | Holthe, M, Rakvag, T N, Klepstad, P, Idle, J R, Kaasa, S, Krokan, H E, Skorpen, F |
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| Zdroj: | Pharmacogenomics Journal; 2003, Vol. 3 Issue 1, p17, 10p, 7 Charts, 5 Graphs |
| Abstrakt: | Focuses on a study which examined the impact of uridine 5'-diphosphate-glucuronosyltransferase 2B7 gene variants on the catalysis of morphine glucuronidation in cancer patients. Materials and methods; Results; Discussion. |
| Databáze: | Complementary Index |
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