| Autor: |
Ghanaati, Shahram, Barbeck, Mike, Willershausen, Ines, Thimm, Benjamin, Stuebinger, Stefan, Korzinskas, Tadas, Obreja, Karina, Landes, Constantin, Kirkpatrick, Charles J., Sader, Robert A. |
| Předmět: |
|
| Zdroj: |
Clinical Implant Dentistry & Related Research; Dec2013, Vol. 15 Issue 6, p883-892, 10p |
| Abstrakt: |
Purpose: In this study the de novo bone formation capacity of a nanocrystalline hydroxyapatite bone substitute was assessed 3 and 6 months after its insertion into the human sinus cavity. Materials and Methods: Sinus cavity augmentation was performed in a total of 14 patients ( n = 7 implantation after 3 months; n = 7 implantation after 6 months) with severely atrophic maxillary bone. The specimens obtained after 3 and 6 months were analyzed histologically and histomorphometrically with special focus on bone metabolism within the residual bone and the augmented region. Results: This study revealed that bone tissue formation started from the bone-biomaterial-interface and was directed into the most cranial parts of the augmented region. There was no statistically significant difference in new bone formation after 3 and 6 months (24.89 ± 10.22% vs 31.29 ± 2.29%), respectively. Conclusions: Within the limits of the present study and according to previously published data, implant insertion in regions augmented with this bone substitute material could be considered already after 3 months. Further clinical studies with bone substitute materials are necessary to validate these findings. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
Plný text