Identification of an amino acid-base contact in the GCN4-DNA complex by bromouracil-mediated...

Autor: Blatter, Erich E., Ebright, Yon W.
Předmět:
Zdroj: Nature; 10/15/1992, Vol. 359 Issue 6396, p650, 3p, 1 Color Photograph, 2 Black and White Photographs, 4 Diagrams
Abstrakt: Presents evidence for the induced helical fork model of the bZIP DNA-binding proteins. Best characterized bZIP DNA-binding protein is GCN4, a yeast transcriptional activator; Site GCN4 binds to; Details of proposed induced helical fork model; Use of site-specific bromouracil-mediated photocrosslinking method; Position of the alanine on GCN4; Details on site-specific bromouracil-mediated photocrosslinking method.
Databáze: Complementary Index