New facile one-pot synthesis of S-alkyl thiolcarbamates from xanthogenate in water.

Autor: Milosavljević, Milutin M., Mijin, Dušan Ž., Milisavljević, Smiljka S., Elezović, Nataša M., Milanović, Jelena K.
Zdroj: Chemical Monthly / Monatshefte für Chemie; Dec2013, Vol. 144 Issue 12, p1833-1837, 5p
Abstrakt: A simple and efficient one-pot synthesis was developed for the preparation of S-alkyl thiolcarbamates from xanthogenate without catalyst using water as a solvent. The water can be recycled after removal of the product. The significant features of this protocol are: operational simplicity, mild reaction conditions, recycling of solvent and high product yields. Starting basic alkyl xanthogenate reacts with alkyl ammonium sulfate (aryl ammonium sulfate) and hydrogen peroxide (molar ratio 1:0.55:1) in water at 40 °C for 1 h, followed by additional heating at 70–110 °C for 1–2.3 h. Good to excellent yields were achieved using ammonium sulfate in 10 % molar excess. Graphical abstract: [Figure not available: see fulltext.] [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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