| Autor: |
Patil, Shankargouda, Rao, Roopa S., Ganavi, B. S. |
| Předmět: |
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| Zdroj: |
Journal of International Oral Health; Sep/Oct2013, Vol. 5 Issue 5, p146-149, 4p |
| Abstrakt: |
Giant cells are the soldiers of defensive system of our body. They differ based on the stimuli that provoked their formation. On the other hand, squamous cell carcinoma (SCC) being the most common oral cancer, presents with varied histopathological features based on the degree of differentiation. Keratinizing islands of dysplastic squamous epithelial cells & a dense inflammatory response form the major component of well differentiated SCC. This keratin component may sometimes trigger foreign body giant cell (FBGC) reaction in the stroma, which may mislead the pathologist to aggressive forms of SCC containing pleomorphic giant cells. We encountered such an interesting case of foreign body giant cell reaction in oral SCC. Thus, the present article aims to provide a thorough knowledge on FBGC including their appearance, pathogenesis & significance in oral SCC. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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