Systematic Review of Blood Biomarkers in Cystic Fibrosis Pulmonary Exacerbations.

Autor: Hakimi Shoki, Alborz, Mayer-Hamblett, Nicole, Wilcox, Pearce G., Sin, Don D., Quon, Bradley S.
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Zdroj: CHEST; Nov2013, Vol. 144 Issue 5, p1659-1670, 12p
Abstrakt: The article discusses a study on the systematic review of blood-based biomarkers in cystic fibrosis pulmonary exacerbations (CFPE). The researchers studied a number of blood-based biomarkers including inflammatory cytokines, acute phase reactants and markers of oxidative stress. Results revealed the correlation of C-reactive protein with disease activity and changes in response to CFPE treatment. Several potential biomarkers were identified such as lactoferrin, calprotectin and myeloperoxidase.
Databáze: Complementary Index