| Autor: |
Desai, D. G., Seth, A. K., Molvi, K. I., Mansuri, M. M., Prajapati, B. R. |
| Předmět: |
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| Zdroj: |
Pharma Science Monitor; Apr2012, Vol. 3 Issue 2, p133-141, 9p |
| Abstrakt: |
The Ni(II) complex of novel, 2-(1-(substituted)-5-nitro-1H-imidazol-2-yl)-1-(substituted) ethanone have been synthesized and characterized by FTIR, molar conductivity, 1HNMR, MASS. Novel 2-nitroimidazole act as a bidentate ligand through the 3-N of imidazole ring and C=O, at 2-position of nitroimidazole, which coordinate the metal ion give rise to 4-coordinate tetrahedral Ni(II) complex. The in vitro antimicrobial activity was determined by using cylinder plate method. The compounds were found to be more active than ligand against Gram-positive bacteria, B. Pumilus ATCC 14884, S. aureus ATCC 29737 and Gram negative bacteria, S. aboney NCTC 6017. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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