APR-246/PRIMA-1MET inhibits thioredoxin reductase 1 and converts the enzyme to a dedicated NADPH oxidase.

Autor: X. Peng, M.-Q.-Z. Zhang, Conserva, F., Hosny, G., Selivanova, G., Bykov, V. J. N., Arnér, E. S. J., Wiman, K. G.
Zdroj: Cell Death & Disease; 2013, Vol. 4 Issue 10, p1-7, 7p
Databáze: Complementary Index